Recombinant CD48 anticorps

N° du produit ABIN7543023

L’anticorps Lapin Chimeric anti-CD48 a été validé pour FACS et BP. Il convient pour détecter CD48 dans des échantillons de Rat.

Aperçu rapide pour Recombinant CD48 anticorps (ABIN7543023)

Antigène: CD48

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD48 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Peptide (BP)

Clone: OX-45

Détail du produit anti-CD48 anticorps

Fonction: Anti-CD48 [OX-45], Rabbit IgG, kappa

Specificité: OX-45 binds specifically to CD48 on rat thymocytes, T and B cells and endothelium but not LFA.3. Directly competes with CD46 for binding the target epitope. CD48 is a CD2 ligand and is expressed on the surface of all hematopoietic cells and endothelium. May be involved in the facilitation of interactions between activated lymphocytes. Likely to be involved in T cell activation.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: OX-45 was prepared by immunizing BALB/c mice with rat T blasts prepared by stimulating purified T helper (TH) cells with allogeneic irradiated rat spleen cells.

Isotype: IgG kappa

Information d'application

Indications d'application: Describes the use of OX-45 in blocking the primary mixed lymphocyte response (MLR)and the secondary response of T lymphocytes to the soluble antigen DNP-BGG. It also showed that OX-45 did not have any effect on the cytotoxic activity of specific (CTL) or non-specific (NK) killer cells or on proliferative responses stimulated by lectins or oxidative mitogenesis.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD48

Antigène: CD48

Autre désignation: CD48

Sujet: BCM1, BCM1 surface antigen, BLAST1, BLAST-1, HM48-1, MRC OX-45 surface antigen, MRC OX45 surface antigen, OX45 surface antigen, OX-45 surface antigen, SLAM family member 2, SLAMF2, sgp60, sgp-60, signalling lymphocytic activation molecule 2 OX45, MRC OX-4

UniProt: P10252